Monday, April 13, 2015

Week 12: Definitions



Hypersensitivity: Any immune response against a foreign antigen that is exaggerated beyond the norm. 

There are four types of hypersensitivity and it's associated diseases or conditions:

  • Type I Hypersensitivity
    • Allergies: An immediate hypersensitivity response against an antigen. 
  • Type II Hypersensitivity
    • Immune Thrombocytopenic Purpura: Disease resulting when drugs bound to platelets bind antibodies and complement, causing the platelets to lyse. 
  • Type III Hypersensitivity
    • Glomerulonephritis: Deposition of immune complexes in the walls of the glomeruli--networks of minute blood vessels in the kidneys--that may result in kidney failure; typically caused by infection with group A Streptococcus
  • Type IV Hypersensitivity
    • Allergic Contact Dermatitis: Type of delayed hypersensitivity reaction in which chemically modified skin proteins trigger a cell-mediated immune response. 
*allergic contact dermatitis 

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